Inflammation, C-Reactive Protein, and Cardiovascular Disease
نویسندگان
چکیده
منابع مشابه
C-reactive protein and cardiovascular disease.
Paul M Ridker, MD, MPH, and Nader Rifai, PhD, eds 393 pages. St-Laurent, Canada: MediEdition Inc; 2006. $68.99. ISBN 0-9780090-0-2. Few biomarkers of disease have generated as much interest, promise, and debate as C-reactive protein (CRP). CRP, a hepatically derived pentraxin, was discovered in 1930 by Rockefeller University investigators William Tillett and Thomas Francis in patients with pneu...
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In the present issue, Chew and colleagues 1 show that elevated baseline C-reactive protein (CRP) levels before percutaneous coronary intervention (PCI) are associated with a progressive increase in the risk of death or myocardial infarction at 30 days. The independent association of risk attributable to the marker CRP remained, even after adjusting for a number of baseline variables that are kn...
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C-reactive protein (CRP), a blood marker of inflammation and a hallmark of the acute-phase response, has been shown to be a powerful and specific predictor of cardiovascular event risk in populations of otherwise healthy persons. Here we review what is known about CRP gene polymorphisms, discuss how these might affect the epidemiology of CRP and our understanding of CRP's contribution to cardio...
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T wenty years ago, investigators collaborating in the laboratory of Attilio Maseri made the observation that plasma levels of the inflammatory biomarkers C-reactive protein (CRP) and serum amyloid A are elevated in patients with severe unstable angina, and that those with higher levels have worse clinical outcomes. 1 However, as concentrations of CRP, serum amyloid A, and other acute phase reac...
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The major public health concern worldwide is coronary heart disease, with dyslipidemia as a major risk factor. Statin drugs are recommended by several guidelines for both primary and secondary prevention. Rosuvastatin has been widely accepted because of its efficacy, potency, and superior safety profile. Inflammation is involved in all phases of atherosclerosis, with the process beginning in ea...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2014
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.114.303215